Subrata Ghosh

Senior Professor 


E-Mail :ocsg [at] iacs.res.in

Short Bio-data :

Subrata Ghosh received his B.Sc. with Honors in Chemistry and M.Sc. with specialization in Organic Chemistry from University of Calcutta. In 1974 he joined the Department of Organic Chemistry, Indian Association for the Cultivation of Science, Calcutta for doctoral research under the supervision of Professor U.R. Ghatak. Based on his work on synthetic studies in gibberellins using the chemistry of a-diazocarbonyl compound he was awarded with Ph.D. degree of Calcutta University in 1978. He did his post-doctoral research with Professor R.G. Salomon of Case Western Reserve University, USA, during the years 1979-1981 and 1984-1986 on photocycloaddition reaction and synthesis of levugladins. In 1982, he joined the faculty of organic chemistry at IACS as Lecturer, where he is presently Professor of Organic Chemistry. He was a Visiting Professor at the University of Leicester, England from October-December, 1997.
 

Award/Fellowship of learned bodies :

  • Fellow of the Indian Academy of Sciences (Bangalore)
  • Fellow of the West Bengal Academy of Science and Technology

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    Current Research Interests :

    Asymmetric synthesis, development of new synthetic methodologies, total synthesis of natural products, cycloaddition reactions and reaction mechanism.
     

    List of Selected Recent Publications :

    1.  “Synthesis of Fused Cyclic Systems Containing Medium-Sized Rings through Tandem ROM-RCM of Norbornene Derivatives Embedded in a carbohydrate Template”, C. K. Malik, R. N. Yadav, M. G. B. Drew, S. Ghosh, J. Org. Chem., (2009), 74, 1957. 

    2. “A Novel Asymmetric Approach to a Densely Functionalized Lactarane Ring System Through a Domino Ring Opening-Ring Closing Metathesis of a Norbornene Derivative”, S. Mondal, C. K. Malik, S. Ghosh Tetrahedron Lett., (2008), 49, 5649. 

    3. “A Simple Route to the Syntheses of of Both Enantiomers of trans-Oak lactone and (+)-cis-Oak lactone” M. Ghosh, S. Bose, S. Ghosh, Tetrahedron Lett., (2008), 49, 5424. 

    4. “A Stereocontrolled Approach for the synthesis of 2,5-Diaryl-3,4-Disubstituted Furano Lignans through a Highly Diastereoselective Aldol Condensation of an Ester Enolate with an a-Chiral Center: Total Syntheses of (-)-Talaumidin, and (-)-Virgatusin”, K. Matcha and S. Ghosh, Tetrahedron Lett. (2008), 49, 3433. 

    5. ‘Rapid Assembly of the Functionalized Tricyclic Core of Umbellactal through Domino Metathesis Involving ROM-RCM of a Norbornene Derivative’ S. Maity, S. Ghosh, Tetrahedron Lett. (2008), 49, 1133.  

    6. ‘Domino Metathesis Involving ROM-RCM of Substituted Norbornenes. Rapid Access to Densely Functionalized Tricyclic Bridged and Condensed Ring Systems’, C. K. Malik, S. Ghosh, (2007), Org. Lett., 9, 2537. 

    7 ‘The First Total Synthesis of Sequosempervirin A through an Orthoester Claisen Rearrangement-Ring Closing Metathesis Sequence’, S. Maity, S. Ghosh, Tetrahedron Lett., (2007), 48, 3355. (Within Top 25 most cited papers). 

    8. ‘Copper (I) Catalyzed [2+2] Photocycloaddition of Non-conjugated Alkenes in Room Temperature Ionic Liquids’, C. K. Malik, M. Vaultier, S. Ghosh, Synthesis (2007), 1247 (special topic on copper in organic synthesis on invitation by Eric Carriera). 

    9. A Convenient Approach for Access to Both Carbapentofuranoses and Carbahexo-pyranoses. Stereocontrolled Synthesis of Enantiopure Carba-D-ribofuranoses, Carba-D-arabinofuranoses and Carba-L-gulopyranose’, S. Ghosh ,T. Bhaumik, N. Sarkar, A. Nayek , J. Org. Chem., (2006), 71, 9687. 

    10. ‘Stereodivergent Approach to the Asymmetric Synthesis of Bacillariolides: A Formal Synthesis of ent-Bacillariolide II’, S. Ghosh, S. Sinha, M. G. B. Drew, Org. Lett., (2006), 8, 3781. 

    11 ‘Convenient Route to Both Enantiomers of a Highly Functionalized Trans-Disubstituted Cyclopentene. Synthesis of the Carbocyclic core of the Nucleoside BCA’,  S. Banerjee, Sarita Ghosh, S. Sinha, Subrata Ghosh, J. Org. Chem. (2005), 70, 4199.

    12. ‘Alkoxy Group Facilitated Ring Closing Metathesis (RCM) of Acyclic 1, 6-Dienes. Convenient Synthesis of Non-racemic Highly Substituted Cyclopentenols’, A. Nayek, S. Banerjee, S. Sinha, S. Ghosh, Tetrahedron Lett., (2004), 45, 6457. 

    13. ‘Copper(I)-catalyzed Intramolecular Asymmetric [2+2] Photocycloaddition. Synthesis of Both Enantiomers of Cyclobutane Derivatives’, N. Sarkar, A. Nayek, S. Ghosh, Organic Letters, (2004), 6, 1903.  

    14. ‘Intramolecular [2+2] Photocycloaddition of Alkenes Incorporated in Carbohydrate Template. Synthesis of Enantiopure Bicyclo[3.2.0]heptanes and[6.3.0]undecanes’, S. P. Banerjee, S. Ghosh, J. Org. Chem., (2003),  68, 3981. 

    15. ‘Enantiospecific Synthesis of (+)-Herbertene’, A. Nayek, S. Ghosh, Tetrahedron Lett., (2002), 43, 1313. 

    16. ‘A New Stereoselective Route to Carbocyclic Nucleoside Cyclobut-A’, J. Panda, S. Ghosh, S. Ghosh, J. Chem. Soc. Perkin Trans.1, (2001),  4013. 

    17. ‘Intramolecular [2+2] Photocycloaddition of 1,6-Dienes Incorporated in a Furanose Ring. Unusual Formation of cis-syn-cis6-oxatricyclo[6.2.0.0]decanes’, S. Ghosh, S. P. Banerjee, K. Chowdhury, M. Mukherjee, J. A. K. Howard, Tetrahedron Lett., (2001), 42, 5997.  

    18. ‘The Stereoselective Preparation of Enantiomerically Pure Annulated Carbohydrates Using Ring Closing Metathesis’, D. J. Holt, W.D. Barker, P.R. Jenkins, J. Panda and S. Ghosh, J. Org. Chem., (2000), 65, 482. 

    19. ‘The Cu(I) Catalysed [2+2] Intramolecular Photoannulation of Carbohydrate Derivatives’, D.J. Holt, W. Barker, P.R. Jenkins, S. Ghosh, D.R. Russell, J. Fawcett, Synlett, (1999), 1003.  

    20. ‘Facile Annulation of Six-Membered Rings onto Carbohydrate Template Based on Ring Closing Metathesis. Synthesis of Enantiopure Bicyclic Ethers’, J. Panda, A. Haque, S. Ghosh, Indian J. Chem., (1999), 38B, 8.   

    21. J. Panda and S. Ghosh, (1999), ‘Intramolecular [2+2] Photocycloaddition for the Direct Synthesis of Cyclobutane Fused g-Lactols’, Tetrahedron Lett., 40, 6693.

    22. ‘Stereocontrolled Total Synthesis of b-Necrodol’, S. Samajdar, A. Ghatak and S. Ghosh, Tetrahedron Lett., (1999), 40, 4401. 

    23., ‘Ring Closing Metathesis in Carbohydrate Annulation’, D.J. Holt, W.D. Barker, P.R. Jenkins, D.L. Davies, S. Garatte, J. Fawcett, D.R. Sussell and S. Ghosh, Angew Chem. Int. Ed. Engl., (1998), 37, 3298.  

    24. ‘Samarium(II) Iodide Promoted Carbon-Carbon Bond Fragmentation : A Facile Route to Bridged Eight Membered Rings and 1,3-Disubstituted Cyclopentanes’, A. Haque and S. Ghosh, J. Chem. Soc., Chem. Commun., (1997), 2039.  

    25. ‘A Facile Access to Densely Functionalized Substituted Cyclopentanes and Spiro Cyclopentanes. Carbocation Stabilisation Directed Bond Migration in Rearrangement of Cyclobutanes’, A. Haque, A. Ghatak, S. Ghosh and N. Ghoshal J. Org. Chem., (1997), 62, 5211. 

    26. ‘Intramolecular [2+2] Photocycloaddition – Cyclobutane Rearrangement. A Novel Stereocontrolled Approach to Highly Substituted Cyclopentanones’, S. Ghosh, D. Patra and S. Samajdar, Tetrahedron Lett., (1996), 37, 2073. 

    27. ‘Synthesis of Cyclopentanoids – A Never Ending Challenge’, S. Ghosh and D. Patra, Pure and Appl. Chem., (1996), 68, 597.

    28. ‘A Short Synthesis of (±)-Methylenolactocin’, S. Sarkar and S. Ghosh, Tetrahedron Lett., (1996), 37, 4809. 

    29. ‘Stereoselectivity and Stereospecificity in a Contrastereoelectronically Controlled Pinacol Rearrangement of Alkoxycyclobutane Derivatives. A Novel Route to Vicinally Substituted Cyclopentanones’, D. Patra and S. Ghosh, J. Org. Chem., (1995), 60, 2526.  

    30. ‘A Novel Route to Usefully Functionalised Spiro[n.4]systems. Application to a Formal Synthesis of (±)a-Cedrene’’, S. Ghosh, D. Patra and G. Saha, J. Chem. Soc., Chem. Commun., (1993), 783.


     

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    Updated On 08-05-2009